M10.2 MSDS and Toxnet

A chemical I looked up that we handle often in the workplace is Naloxone. This is a drug used to stop opioid overdoses. This is what I found:


LD50 LC50 Mixture:LD50 (ORAL RAT) IS 1200 MG/KG(FREE BASE)
Routes of Entry: Inhalation:NO Skin:NO  Ingestion:NO
Reports of Carcinogenicity: NTP:NO    IARC:NO OSHA:NO
Health Hazards Acute and Chronic: SINCE PRODUCT IS FORMULATED FOR HUMAN
    THERAPEUTIC USE AND CONTAINS < 1% ACTIVE INGREDIENT BY VOLUME,
    NORMAL HANDLING IS NOT EXPECTED TO CONSTITUTE A HAZARD.
Explanation of Carcinogenicity: THIS COMPOUND CONTAINS NO INGREDIENTS AT
    CONCENTRATIONS OF 0.1% OR GREATER THAT ARE CARCINOGENS OR SUSPECT
    CARCINOGENS.
Effects of Overexposure:CLINICAL EXPERIENCE WITH PRODUCT HAS FOUND THAT
    IN THE ABSENCE OF NARCOTICS, PRODUCT EXHIBITS ESSENTIALLY NO
    PHARMACOLOGIC ACTIVITY.
Medical Conditions Aggravated by Exposure: NONE SPECIFIED BY MANUFACTURER.


Overall this sounds like good news! There are no carcinogens at concentrations higher than 0.1%, there is no detected hazardous effect from overexposure, and normal handling of it is not expected to pose a hazard.

Comments

  1. Sandy TanNovember 1, 2018 at 10:08 AM

    Hi Hugo,
    I did not know there was a drug to stop opioid overdoses! I am glad to learn that there are no carcinogens, because it would be dangerous for the people who take those drugs.

    ReplyDelete
  2. USF MPH ClassNovember 16, 2018 at 6:17 PM

    Hi,
    This is a well know drug in the RN community. I am so glad it is here to help the overdoses. Do you think cops and firefighters should carry them or not? Would like to know your opinion on the access of this drug for emergencies. Dan

    ReplyDelete

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